Owkin Virtual StainingAutomated Immunostainings
We are developing a technology platform to enable every pathologist and translational researcher to use immunohistochemical & immunofluorescence stainings.
Generate immunostained slides with machine learning
Owkin Virtual Staining allows you to automatically compute a virtual immunostained slide from a digitized H&E stained specimen slide.
Owkin has developed a deep learning data enrichment model that can produce virtual immunostains from existing H&E whole slide images.
It leverages state-of-the-art generative adversarial networks that learn from double or multiplex stained histopathology slides. It enables the model to generate, in a click, immunostaining for any H&E slide, bypassing wet lab work.
GET IN TOUCHVirtual staining in action in Owkin Studio
The virtual staining technology is integrated in Owkin Studio, our machine learning platform for researchers.
Here, we demonstrate the creation of a virtual CD3 stained slide from an original digitized H&E slide. CD3 marker allows identification & quantification of T-cells, and analysis of immune infiltration of the tumor microenvironment. The CD3 stain has high prognostic value, as T-cell activation is linked to overall immune response.
Learn more about virtual staining
Virtual staining is a core project at Owkin, aimed at augmenting the predictive power of our models, improve our interpretability features, and deepen our digital histopathology collaborations.
Read the story of how our virtual staining technology was developed in a featured blog post.
Request access to the technical white paper on CD3 virtual stain.
BLOG POST WHITEPAPEROwkin immunochemistry & immunofluorescence pipeline
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Hear from our Users
“Virtual staining is a toolkit technology. It allows us to augment our pathology data, unveil new signal and insights, and thus improve diagnostic power and enrich research”
Clinical pathologist – Liver expert
Technical requirements
For use in research setting only
- Compatible with all standard digital pathology file formats (svs, tiff, tif, support of all major vendors)
- Inference requires access to GPU compute
- On-premise or cloud-based deployment
- Virtual staining is available in Owkin Studio
- Integration with specific digital pathology workflows and softwares available upon request